What is Acne ?
Acne is a disorder resulting from the action of
hormones and other substances on the skin's oil glands
(sebaceous glands) and hair follicles. These factors lead to
plugged pores and outbreaks of lesions commonly called
pimples or zits. These normally occur on the face,
neck, back, chest, and shoulders. Although it is
usually not a serious health threat, it can be a source of
significant emotional distress. If it is severe, it
can lead to permanent scarring. I'm sure you already
know that and would like to do something about it. The
following information will help you ...
How Does Acne
Develop?
Doctors describe this skin disorder as a
disease of the pilosebaceous units (PSUs). Found over most of
the body, PSUs consist of a sebaceous gland connected to a
canal, called a follicle, that contains a fine hair (see
"Normal Pilosebaceous Unit" diagram). These units are most
numerous on the face, upper back, and chest. The sebaceous
glands make an oily substance called sebum that normally
empties onto the skin surface through the opening of the
follicle, commonly called a pore. Cells called keratinocytes
line the follicle.
| Normal Pilosebaceous Unit |
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The hair, sebum, and keratinocytes that fill
the narrow follicle may produce a plug, which is an early sign
of acne. The plug prevents sebum from reaching the surface of
the skin through a pore. The mixture of oil and cells allows
bacteria Propionibacterium acnes (P. acnes) that
normally live on the skin to grow in the plugged follicles.
These bacteria produce chemicals and enzymes and attract white
blood cells that cause inflammation. (Inflammation is a
characteristic reaction of tissues to disease or injury and is
marked by four signs: swelling, redness, heat, and pain.) When
the wall of the plugged follicle breaks down, it spills
everything into the nearby skin – sebum, shed skin cells, and
bacteria – leading to lesions or pimples ...
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Acnezine
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Acne
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